Xylocaine 2% Standard Cartridges - 2.2ml (50)

Xylocaine 2% with Adrenaline (Epinephrine) 1:80,000 - 2.2ml Cartridges (50)

Xylocaine - Lidocaine Hydrochloride local anaesthetic

Xylocaine 2% with Adrenaline (Epinephrine) 1:80,000 for dental local anaesthesia. 30mg/ml + 12.5 microgram/ml lidocaine hydrochloride + adrenaline in packs of 50 standard cartridges.

Xylocaine Production & Packaging

Dentsply Sirona ensure quality at each step of Xylocaine's product journey from collection of active molecule till it reaches your dental practice.

Each Xylocaine cartridge is twice sterilized with sterilizing filter followed by autoclave method. Cartridges are then visually inspected with electronic laser for defects and impurities including but not limited to cracks, foreign particles, colour and density.

Each cartridge is Mylar pack labeled to restrain the individual pieces in case of a break thus avoiding any injuries. Each set of 10 cartridges is then blister packed to avoid breakage.

Each cartridge is colour coded as per industry standard.

Xylocaine Indications

In case of infiltration onset duration is less than 2 minutes with soft tissue anaesthesia lasting 2.5 hours to 3.25 hours for infiltration and nerve block respectively. 

Xylocaine is contra indicated in patients who are hypersensitive to local anesthetics.

Xylocaine should not be used in patients with congenital or idiopathic methemoglobinemia. Common precautions include aspiration prior to injection to help avoid intravascular injection. Local anaesthetic solutions like Xylocaine that contain a vasoconstrictor should be used cautiously especially in patients with impaired cardiovascular function or vascular disease. 

Lignocaine is classed as a membrane stabilising agent, and is a local anaesthetic of the amide type. Lignocaine stabilises the neuronal membrane and reversibly prevents the initiation and conduction of nerve impulses thereby producing local anaesthesia. The onset and duration of anaesthesia depend on the route of administration and the dosage (volume and concentration) employed. The addition of adrenaline reduces the rate of absorption of lignocaine from the site of injection, thereby increasing the duration of action.

What does Xylocaine 2% with Adrenaline (epinephrine) 1:80,000 contain?

Each ml of Xylocaine solution contains:

• Lidocaine Hydrochloride equivalent to lidocaine hydrochloride anhydrous 20 mg (44 mg per 2.2 ml cartridge).
• Adrenaline (Epinephrine) tartrate equivalent to adrenaline (epinephrine) 12.5 micrograms (27.5 micrograms per 2.2 ml cartridge).

The other ingredients of Xylocaine are:

• Sodium chloride.
• Sodium metabisulfite (E223).
• Sodium hydroxide.
• Hydrochloric acid.
• Water for injections.

What does Xylocaine® 2% with Adrenaline (epinephrine) 1:80,000 look like and what are the contents of the pack?

Xylocaine is a clear, colourless, aqueous sterile solution.

• Solution for injection for dental use.
• Each glass cartridge contains 2.2ml of Xylocaine® 2% with Adrenaline (epinephrine) 1:80,000 DENTAL.
• Each pack contains 50 cartridges.

How to store Xylocaine® 2% with Adrenaline (epinephrine) 1:80,000

• Keep out of the sight and reach of children.
• Do not store above 25ºC.
• Do not freeze.
• Keep the container in the outer carton in order to protect from light.
• Do not use Xylocaine® 2% with Adrenaline (epinephrine) 1:80,000 DENTAL after the expiry date which is printed on the container after EXP.
• The expiry date refers to the last day of the month.
• Do not use if there is any appearance of cloudiness or colour.

Contents

• Box of 50 x 2.2ml glass cartridges of Xylocaine 2% with Adrenaline (epinephrine) 1:80,000 DENTAL.

References and useful links for more information on Xylocaine® 2% with Adrenaline (epinephrine) 1:80,000:

• National Institute for Health and Care Excellence (NICE): https://bnf.nice.org.uk/drugs/lidocaine-with-adrenaline/medicinal-forms/
• NHS: https://dmd-browser.nhsbsa.nhs.uk/ampp/view/195681?ref=
• NHS - Dental Therapists & Hygienists: https://www.england.nhs.uk/long-read/supply-and-administration-of-medicines-by-dental-hygienists-and-dental-therapists/
• Report an issue with a medicine to the MHRA Yellow Card scheme: https://yellowcard.mhra.gov.uk/